讲授课程

本科生：基础有机化学（I）

研究生: 金属有机化学

研究兴趣

有机合成化学：杂环化合物的合成，天然产物的全合成，药物的新法合成；

金属有机化学：过渡金属催化偶联反应🤛🏻，有机金属试剂的制备及反应。

招生方向

过渡金属催化与有机合成

代表性论文

1. Xia, D.; Duan, X. F.* Alkylative Dearomatization by Using an Unactivated Aryl Nitro Group as a Leaving Group: Access to Diversified Alkylated Spiro[5.5]trienones, Org. Lett. 2021, 23, 2548.
2. Xia, D.; Duan, X. F.* Iron-Catalyzed Dearomatization of Biaryl Ynones with Aldehydes via Double C−H Functionalization in Eco-Benign Solvents: Highly Atom-Economical Synthesis of Acylated Spiro[5.5]trienones, J. Org. Chem. 2021, 86, 15263.
3. Wei, Y. M.; Ma, X. D.; Wang, L.; Duan, X. F.* Iron-catalyzed stereospecific arylation of enol tosylates using Grignard reagents, Chem. Commun., 2020, 56, 1101.
4. Duan, X. F.* Iron catalyzed stereoselective alkene synthesis: a sustainable pathway Chem. Commun., 2020, 56, 14937 (Feature Article).
5. Wei, Y. M.; Wang, M. F.; Duan, X. F.* Is Fe-catalyzed ortho C−H Arylation of Benzamides Sensitive to Steric Hindrance and Directing Group? Org. Lett. 2019, 21, 6471.
6. Wang, L.; Wei, Y. M.; Zhao, Y.; Duan, X. F.* Unified Protocol for Fe-Based Catalyzed Biaryl Cross-Couplings between Various Aryl Electrophiles and Aryl Grignard Reagents. J. Org. Chem. 2019, 84, 5176.
7. Xu, L. C; Liu, K. M.; Duan, X. F.* Iron-Catalyzed Room Temperature Cross-Couplings of Bromophenols with Aryl Grignard Reagents, Adv. Synth. Catal. 2019, 361, 5421 (Highlighted by Org. Process Res. Dev.).
8. Zhang, R.; Zhao, Y.; Liu, K. M.; Duan, X. F.* Phenolate Enabled General and Selective Fe/Ti Cocatalyzed Biaryl Cross-Couplings between Aryl Halides and Aryl Grignard Reagents, Org. Lett. 2018, 20, 7942 (Highlighted by Synfacts and Org. Process Res. Dev.)
9. Wei, J. Liu, K. M.; Duan, X. F.* Cobalt-Catalyzed Biaryl Couplings via C−F Bond Activation in the Absence of Phosphine or NHC Ligands, J. Org. Chem. 2017, 82, 1291 (Cover Art, Highlighted by Synfacts and Org. Process Res. Dev.).
10. Liu, K. M.; Liao, L. Y.; Duan, X. F.* Iron catalyzed oxidative assembly of N-heteroaryl and aryl metal reagents using oxygen as an oxidant, Chem. Commun., 2015, 51, 1124 (Highlighted by Synfacts).
11. Liu, K. M.; Wei, J.; Duan, X. F.* Iron-catalyzed oxidative biaryl cross-couplings via mixed diaryl titanates: significant influence of the order of combining aryl Grignard reagents with titanate, Chem. Commun., 2015, 51, 4655.
12. Liao, L. Y.; Liu, K. M.; Duan, X. F.* Unified Protocol for Cobalt-Catalyzed Oxidative Assembly of Two Aryl Metal Reagents Using Oxygen as an Oxidant, J. Org. Chem. 2015, 80, 9856 (Feature Article).
13. Liao, L. Y.; Kong, X.-R.; Duan, X. F.* Reductive Couplings of 2‑Halopyridines without External Ligand: Phosphine-Free Nickel-Catalyzed Synthesis of Symmetrical and Unsymmetrical 2,2′-Bipyridines, J. Org. Chem. 2014, 79, 777.
14. Zhang, S.; Liao, L. Y.; Zhang, F.; Duan, X. F.* Arylation, Alkenylation, and Alkylation of 2‑Halopyridine N‑Oxides with Grignard Reagents: A Solution to the Problem of C2/C6 Regioselective Functionalization of Pyridine Derivatives, J. Org. Chem. 2013, 78, 2720 (Highlighted by Synfacts).
15. Zeng, J.; Liu, M. K.; Duan, X. F.* Selective Co/Ti Cooperatively Catalyzed Biaryl Couplings of Aryl Halides with Aryl Metal Reagents, Org. Lett. 2013, 15, 5342 (Highlighted by Synfacts).